Nifediine is a calcium slow-channel blocker and an antianginal drug
             that selectively inhibits the influx of calcium ions into both cardiac
             muscle. In addition it dilates arteries and arterioles of the heart and
             inhibits coronary spasms, which improves oxygen delivery. In addition it
             has a mild effect on systolic and diastolic blood pressure readings.
             Usually this change is small, i the range of 5 - 10 hg, but sometimes the
             Nifepidine treats vasoplastic angina when that angina has been
             confirmed either by documentation of classical angina pattern; provocation
             of angina with ergonovine, or as confirmed on an angiogram. It treats
             chronic angina when beta-blockers or nitrates have failed or in patients
             who do not tolerate those medications well.
             There are several warnings regarding nifedipine. Some patients
             experience marked drops in low blood pressure, sometimes but not always
             when used in combination with a beta-blocker. Documented incidents of
             severe hypotension followed by myocardial infarction and death from
             nifedipine have been noted, and it should not be used to achieve blood
             pressure reduction. There are no well-done studies demonstrating safety or
             efficacy for nifedipine when used this way and its use for control of
             essential hypertension is contra-indicated. Close monitoring is required
             when a patient taking nifedipine or Procardia also is taking medication to
             In addition there is some clinical evidence that nifedipine or
             Procardia may reduce platelet aggregation. No specific warnings are given
             regarding dental care, although it should be noted that nifedipine has a
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