There are several problems that a cell would face it if were to become
             very large. Among the first of these is being faced with an overload of
             nutrients. All nutrients enter the cell through the cell membrane. The
             larger the cell wall, the more nutrients it will contact; an abundance
             could potentially be available to the cell as they pass through the cell
             membrane. However, the more nutrients arriving, the greater the number of
             chemical reactions needed to process them. Moreover, all the nutrients
             would be arriving simultaneously, putting pressure on the cell structures
             to perform a large number of chemical processes at the same time. While a
             small cell would have insufficient cell membrane to move sufficient raw
             materials to nourish itâ€"that is, to allow it to perform the necessary
             chemical reactions to liveâ€"a really enormous cell would have the opposite
             problem. While the exterior, or cell membrane would increase in size, the
             interior area would expand even more, meaning that the membrane might not
             be able to acquire sufficient raw materials to keep the relatively larger
             volume of the interior supplied. (USC Web site) In addition, there are
             limits to the amount of incoming material that can be handled according to
             the cell's DNA, and limits to the amount of waste material, as well. This,
             too, must exit through the cell membrane. (CSUN Web site)
             An adaptation might be to create inlets' in the cell membrane, much
             like the inlets and bays and harbors on heavily indented coastlines that
             allow more ocean water to touch land; that is, to create in a cell the
             equivalent of a long shoreline, where the extra miles are gained by making
             pockets where the land and water meet. Another possible adaptation would
             be for the cell to separate its nutrient acquisition and waste elimination
             functions, holding them in separate structures and using...