Obesity and Weight Loss

             The Newsweek article, "What You Don't Know About Fat," discusses the
             ways in which fat cells work in the body and explains why fat is so hard to
             lose. Authors Anne Underwood and Jerry Adler begin the article by
             describing the discovery of Leptin, a chemical that regulates the body's
             fat cells. Researchers found that when mice were injected with Leptin they
             were able to eat anything and did not gain weight. researchers found that
             mice who did not produce Leptin ate uncontrollably and became fat, and
             normal mice who received a shot of Leptin lost weight. These discoveries
             seemed as if it were the magic bullet of weight loss, but experts have
             since learned that fat cells are much more complicated and difficult to
             manipulate than they once believed. Fat cells, according to the article,
             are difficult to eliminate because they are a part of the body's mechanisms
             for avoiding starvation. And, once you have fat cells they work overtime
             to maintain themselves and multiply, creating a paradox that the more fat
             you have more fat your body wants to make, and even when people do lose
             weight fat cells work overtime and the weight is harder to keep off. Thus,
             while researchers continue to look for strategies to help obese people lose
             weight, the basic standard holds true: to loose weight, you must eat less
             and exercise more.
             The textbook describes basic methods of scientific inquiry and
             experimentation, and these methods appear to have been used in researching
             the Newsweek article. The article describes tests done on mice to study
             the effects and purposes of Leptin. The researchers observed the behavior
             of the mice, developed a hypothesis about Leptin and its effects on
             obesity, predicting that Leptin and obesity were directly related. They
             tested the hypothesis and confirmed that Leptin was indeed important to the
             growth and development of fat cells. However, the experimental results did
             not prove to ...

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