The Newsweek article, "What You Don't Know About Fat," discusses the
ways in which fat cells work in the body and explains why fat is so hard to
lose. Authors Anne Underwood and Jerry Adler begin the article by
describing the discovery of Leptin, a chemical that regulates the body's
fat cells. Researchers found that when mice were injected with Leptin they
were able to eat anything and did not gain weight. researchers found that
mice who did not produce Leptin ate uncontrollably and became fat, and
normal mice who received a shot of Leptin lost weight. These discoveries
seemed as if it were the magic bullet of weight loss, but experts have
since learned that fat cells are much more complicated and difficult to
manipulate than they once believed. Fat cells, according to the article,
are difficult to eliminate because they are a part of the body's mechanisms
for avoiding starvation. And, once you have fat cells they work overtime
to maintain themselves and multiply, creating a paradox that the more fat
you have more fat your body wants to make, and even when people do lose
weight fat cells work overtime and the weight is harder to keep off. Thus,
while researchers continue to look for strategies to help obese people lose
weight, the basic standard holds true: to loose weight, you must eat less
The textbook describes basic methods of scientific inquiry and
experimentation, and these methods appear to have been used in researching
the Newsweek article. The article describes tests done on mice to study
the effects and purposes of Leptin. The researchers observed the behavior
of the mice, developed a hypothesis about Leptin and its effects on
obesity, predicting that Leptin and obesity were directly related. They
tested the hypothesis and confirmed that Leptin was indeed important to the
growth and development of fat cells. However, the experimental results did
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